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  Home > Current Clinical Trials > Small Animal Surgery
 

Small Animal Surgery

CVMVMC2 - image - 690x350 - lake dog

Welcome to the Small Animal Surgery Studies Page!

If you would like more information about a study, or think you would like to enroll your pet, contact the person listed under the study. You may also Contact Us at the CIC.

Currently open studies:
1. A randomized, placebo-controlled trial to investigate the safety and efficacy or an oral nutraceutical for the treatment of arthritis in client-owned dogs

2. A pilot study to evaluate the effectiveness, safety and acceptability of study drug for the control of pain and inflammation associated with osteoarthritis in dogs under clinical conditions 

A randomized, placebo-controlled trial to investigate the safety and efficacy or an oral nutraceutical for the treatment of arthritis in client-owned dogs

Current Status: Open and enrolling
Principal Investigator: Michael Conzemius, DVM, PhD, DACVS
Contact: Sara Pracht, study technician, at 612-626-3574, prach011@umn.edu

Arthritis is a common problem in the dog and often decreases quality of life. One treatment option often recommended by veterinarians for treating the signs of arthritis is a food supplement called a nutraceutical. The purpose of this study is to test if a new nutraceutical is safe and effective for the treatment of arthritis in the dog. Nutraceuticals are not considered drugs by the FDA and are generally felt to be safe. This is a three group, placebo-controlled study, meaning your dog could receive placebo, a control nutraceutical (Dasuquin®) or the new nutraceutical. The study is also double-blind, meaning neither the owner nor Dr. Conzemius will know which treatment a dog is on until the conclusion of the study.

We are looking for dogs with:

  • obvious lameness and pain
  • not on any pain medications or other nutraceuticals (such as steroids, glucosamine/chondroitin, certain foods)

There are several visits to the study:

  • Enrollment - exam, radiographs to confirm osteoarthritis (OA), blood sampling, and fitting with an accelerometer on a special collar. The dog will wear this collar throughout the study.
  • Day 7 - Recheck to collect accelerometer data and to receive study treatment (placebo, Dasuquin or new nutraceutical). Owners will give tablets at home.
  • Day 30 - Visit to the VMC for exam, complete pain inventory and for us to collect accelerometer data. Study treatment will be refilled.
  • Day 60 - Visit to the VMC for exam, complete pain inventory and for us to collect accelerometer data. Study treatment will be refilled.
  • Day 90 - Final visit to the VMC for exam, complete pain inventory and for us to collect accelerometer data. Owners return any unused tablets at this time.

This study covers costs of all procedures listed above, plus $300 at the conclusion.

If you are interested in participating or in referring a dog for this study, please contact Sara Pracht above.

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A pilot study to evaluate the effectiveness, safety and acceptability of study drug for the control of pain and inflammation associated with osteoarthritis in dogs under clinical conditions.

Current Status: Open and enrolling
Principal Investigator: Michael Conzemius, DVM, PhD, DACVS
Contact:
Sara Pracht, study technician, at 612-626-3574, prach011@umn.edu

 
This is a placebo-controlled, double-blinded study to evaluate a new non-steroidal anti-inflammatory drug (NSAID) in a tablet form. Dogs will receive either the study drug or placebo once daily for 28 days. Double–blinded means that neither the study staff seeing the dogs nor the owners will know which treatment the dog is on. We will measure how lame the dogs are by exam, standard lameness checks, and by gait analysis on a force plate. Study visits include two baseline visits a week or less apart, follow up visits at Day 14 and Day 28. Owners will give the tablets at home and will keep records for us. It will be important that the same owner do this for the month of the study.

All study procedures are provided at no charge and owners who complete the study will receive an additional $300 for their time and trouble. 

We are looking for dogs which have:
  • Osteoarthritis (OA) OA observed in the shoulder, elbow, hip or stifle joint (knee) for at least 3 weeks (presence of OA will need to be confirmed by exam and X-ray at the first visit
  • Other than OA, no neurological or musculoskeletal disorders, chronic pain, or systemic disease that could interfere with the goals of the study
  • No recent surgery on any joint
  • No recent injury to the joint and does not show sigs of cranial cruciate rupture

We will evaluate other criteria at the baseline visits.

Certain medications need to be stopped prior to the study (NSAIDS, corticosteroids, opioids, and others. Please ask about this when calling us.

For more information, please call or email Sara Pracht above.

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