Professor - Veterinary Population Medicine (office: Vet Diagnostic Medicine)

obrie004@umn.edu

Education

• B.S. University of Minnesota (1976)
• D.V.M. University of Minnesota (1978)
• Ph.D. University of Minnesota, (1985)

American College of Veterinary Pathologists (Anatomic Pathology, 1984)

Research Interests

• Development and clinical applications of adult, bone marrow-derived multipotent stem cells.
• Pathogenesis of type 2 diabetes mellitus and relationship to islet amyloid polypeptide (IAPP)-derived islet amyloidosis.

Clinical Interests

• Surgical pathology including oncologic pathology and dermatopathology.

Instructional areas

• Veterinary pathology: amyloidosis, diseases of the urinary tract, & diseases of the endocrine system.
• Surgical and comparative pathology.

Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

Current Funding

• NIH 1U19-DK-61244-01 C.M. Verfaillie (PI), 9/1/01-8/31/06, Beta cell biology consortium: Core D Transplant and imaging core (B.J. Hering, PI)
  Role: Co-Investigator (2%)
  Total Award = $5,560,000
• NIH 1R21-RR021644-01A1 T.D. O¿Brien (PI), 09/22/05-09/30/07, Multipotent Stem Cells from Adult Rhesus Macaques
  Role: Principal Investigator (15% FTE)
  Total Award: $411,125
• CVM Small Companion Animal Grants T.D. O¿Brien (PI), 06/01/05-05/31/06, Development of an in vitro model of cartilage differentiation in 3-dimensional scaffolds using canine multipotent mesenchymal stem cells.
  Role: Principal Investigator. (2% FTE)
  Total award (1 year) = $10,000.

Honors and Awards

• Society of Phi Zeta National Research Award, 1984.
• College of Veterinary Medicine Mark of Excellence Award for Research, 1998

Current Students

• Elizabeth Jones, undergraduate, UROP Program