Credits: 4 credits
Grading Scale: A-F only
Prerequisites: Enrollment in a Ph.D. program, survey courses in biochemistry and cell biology or permission of the course director.
Course Coordinator: Carolyn Fairbanks, Pharmacology; Dr. Dave Brown, Dept. of Veterinary and Biomed. Sci.; firstname.lastname@example.org is the CMB Graduate Program contact faculty.
Course Description: Independent study as determined by instructor. Usual activity includes conduct of research in the instructor’s laboratory.
Statement of Objectives: The objective of this course is to provide the student with a detailed understanding of the pharmaceutical and pharmacological issues specific to direct drug delivery to the CNS. All lectures will emphasize and integrate topics pertinent to neuropharmacology, neuropharmacokinetics and drug delivery. This course is designed for advanced graduate students in neuroscience, pharmaceutics, and related fields of study. The course addresses delivery of compounds to the central nervous system (CNS) to activate proteins in specific brain regions can provide therapeutic benefit, often with reduced side effects relative to systemic delivery. This course provides a detailed description of the pharmaceutical and pharmacological issues specific to direct drug delivery to the CNS.
Course Assignments: As determined by instructor.
Evaluation Procedures: There will be biweekly take-home quizzes on the reading material (20%). There will be one comprehensive review style term paper (35%) and one experimental design project (35%). Class participation (questions, discussions, etc.) will be part of the final evaluation (10%).
Text and Reference Materials: Spinal Drug Delivery, 1st edition; Edited by Tony L. Yaksh. Elsevier, 2002; Manual of Pharmacological Calculations with Computer Programs; Tallarida, R.J., and Murray, R.B.; Springer Verlag: New York 1987; 26-31.
Supplementary Information: This course is crosslisted as Nsc/Phm8481.
Scholastic Dishonesty and Plagiarism:
Students are responsible for knowing the University of Minnesota, Board of Regents' policy on student conduct and scholastic dishonesty: http://www1.umn.edu/oscai/conduct/student/index.html.
Scholastic dishonesty as defined in the policy and will be reported to the Office of Student Judicial Affairs: http://www1.umn.edu/oscai/integrity/scho_dishonest.html and will result in a grade of "F" or "N" for the entire course. Plagiarism is an important element of this policy. It is defined as the presentation of another's writing or ideas as your own. Serious, intentional plagiarism will result in a grade of "F" or "N" for the entire course. For more information on this policy and for a helpful discussion of preventing plagiarism, please consult University policies and procedures regarding academic integrity: http://writing.umn.edu/tww/plagiarism/plagarism_index.html. Students are urged to be careful that they properly attribute and cite others' work in their own writing. For guidelines for correctly citing sources, go to http://tutorial.lib.umn.edu/ and click on “Citing Sources”. In addition, original work is expected in this course. It is unacceptable to hand in assignments for this course for which you receive credit in another course unless by prior agreement with the instructor. Building on a line of work begun in another course or leading to a thesis, dissertation, or final project is acceptable. If you have any questions, consult the instructor.