Professor - University of Montreal

Dr. Marcelo Gottschalk
Department of pathology and microbiology
Faculty of Veterinary Medicine
Université de Montréal
Sicotte St.
St. Hyacinthe (QC)   J2S 2M2
CANADA

Tele: 450-773-8521 ext. 8374
Fax: 450-778-8108
E-mail: marcelo.gottschalk@umontreal.ca

Education
University of Buenos Aires, 1982, DVM, Veterinary Medicine
University of Montreal, 1991, PhD, Microbiology and Immunology

Academic Interests,

• Investigation of the pathogenesis of meningitis caused by Streptococcus and Haemophilus parasuis.
• Development of diagnostic methods for infectious diseases of swine.
• Streptococcus suis: characterization of virulence factors; investigation of the pathogenesis of infection and study of the interactions between bacteria and host phagocytic and non-phagocytic cells (epithelial and endothelial cells); study of strategies to curb infection and investigation of the inflammatory response (cytokines).
• Actinobacillus pleuropneumoniae: antigenic characterization; development of immunological and molecular methods for diagnosing asymptomatic carrier animals.
• Haemophilus parasuis: study of virulence factors and investigation of the pathogenesis of infection, more specifically on meningitis.

Representative Publications

• Chabot-Roy G., P. Willson, M. Segura, S. Lacouture and M. Gottschalk. 2006. Phagocytosis and killing of Streptococcus suis by porcine neutrophils. Microbial Pathogenesis 41: 21-32.
• Segura Segura M., G. Vanier, D. Al-Numani, S. Lacouture, M. Olivier and M. Gottschalk. 2006. Proinflammatory cytokine and chemokine modulation by Streptococcus suis in a whole-blood culture system. FEMS Microbiology Immunology 47: 92-106..
• Vanier G., A. Szczotka, P. Friedl, S. Lacouture, M. Jacques and M. Gottschalk. 2006. Haemophilus parasuis invades porcine brain microvascular endothelial cells. Microbiology 152: 135-142.
• Jacques M., J. Labrie, F. St. Michael, A. D. Cox, M.-A. Paradis, C. P. Dick, C. Klopfenstein, A. Broes, N. Fittipaldi and M. Gottschalk. 2005. Isolation of an atypical strain of Actinobacillus pleuropneumoniae serotype 1 with a truncated lipopolysaccharide outer core and no O-antigen. Journal of Clinical Microbiology 43: 3522-3525.
• Tadjine M., K. R. Mittal, S. Bourdon and M. Gottschalk. 2004. Production and characterization of murine monoclonal antibodies against Haemophilus parasuis and study of their protective role in mice. Microbiology 150: 3935-3945.
• Vanier G., M. Segura, P. Friedl, S. Lacouture and M. Gottschalk. 2004. Invasion of porcine microvascular endothelial cells by Streptococcus suis serotype 2. Infection and Immunity 72: 1441-1449.