Leslie C. Sharkey, College of Veterinary Medicine at the University of Minnesota

Associate Professor - Veterinary Population Medicine (office: Veterinary Diagnostic Labs)

Degrees

B.S. with Honors, University of Michigan 1987
D.V.M. Ohio State University 1993
Ph.D. Ohio State University 1998

Diplomate American College of Veterinary Pathologists (Clinical Pathology)

Research Interests

My research interests include the effects of gender and reproductive status on the development and treatment of cardiovascular disease. I have previously studied the impact of reproductive senescence on the progression of genetically-programmed hypertension and congestive heart failure and have developed rat models for the study of hypertensive disorders of pregnancy. Current projects focus on the study of gender susceptibility to the cardiotoxic chemotherapy drug doxorubicin and the interaction of toxic and genetically programmed cardiovascular disease. In addition, we are studying how the cardiovascular adaptation to pregnancy influences the response to cardiotoxic drugs like doxorubicin.

Clinical Interests

My main clinical interests are improving the diagnostic accuracy of cytology and optimization of the use of clinical chemistry testing as a diagnostic tool.

Instructional areas

I teach cardiovascular pathology and clinical pathology in the veterinary curriculum. My goals are to encourage critical thinking in the diagnostic evaluation of clinical pathology data using a case-based approach. In addition, I try to foster critical thinking in the evaluation of new diagnostic tests and methods.

Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

Current Funding

"Doxorubicin cardiotoxicity: effect of sex and genetic cardiovascular disease" Principle investigator, Graduate School Grant-In-Aid, January 2005-June 2006, $32,000
"Impact of Case-based Writing Assignments and Instructor Feedback on Course Outcomes in Veterinary Clinical pathology" Principal investigator, University of Minnesota Center for Writing 2004-2005, $3500
"Determination of breed-specific reference intervals for assessing thyroid function in Golden Retrieveres, Samoyeds, and Keeshonden, English Setters, Malamutes and Siberian Huskies" AKC Canine Health Foundation, Co-investigator, $88,176 Collaborator

Honors and Awards

1995	Phi Kappa Phi Honor Society
1996	Phi Zeta, The Honor Society of Veterinary Medicine
2001	Basic Science Professor of the Year, Tufts Veterinary School (Teaching award)
2002	Basic Science Professor of the Year, Tufts Veterinary School (Teaching award)
2003	Basic Science Professor of the Year, Tufts Veterinary School (Teaching award)
2003	Nominated by V'O4 for SAVMA Teaching Excellence Award in Clinical Sciences
2004	Recognized for Excellence in Women's Health Research Pregnancy and progesterone exacerbate hypertension in spontaneous hypertension/heart failure rats. Women's Health Research Conference, Minneapolis, MN

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The University of Minnesota is an equal opportunity educator and employer.

Last modified on Thursday Mar 24, 2005

This page is located at http://www.cvm.umn.edu//facultystaff/vpm/sharkey.html