Anatomic pathology as it relates to infectious diseases, agriculture, public health and biomedical research
Our focus is on pain, especially musculoskeletal pain, and depression. We're interested in the role stress hormones, mast cells and TRPV1 receptors play in these two areas.
Our research focuses on the genetic basis and functional analysis of naturally occurring neuromuscular and metabolic disease in horses. Our work includes both diseases that are both clinically and economically important in the horse, as well as the use of the horse as a biomedical model.
My primary research currently is in epilepsy, genetics, metabolic disease, neurologic disorders, molecular medicine, neuromodulation, electrophysiology, and comparative medicine. Much of the research is in naturally occurring canine models for the sake of dogs and as translational for human research including epilepsy, neuropathies, and calcium oxalate urolithasis.
I have been transitioning from a primary focus on reproductive physiology in wildlife to more of a focus on emerging challenges at the intersection of livestock, humans, wildlife and the environment.
I am currently running 3 clinical trials in dogs with brain tumors looking at novel therapies that may translate to human medicine. I also am developing a new model of a chronic critical size defect in goat tibias also to be used the large animal model used to test and compare novel bone regenerative therapies for translation into human orthopedic disease. I am also using a swine model to test treatment of traumatic brain injury and a sheep model of osteoporosis to examine the effects of PTH.
I perform clinical research focused on developing and optimizing diagnostic testing in companion animal species, primarily dogs and cats. My clinical research focuses on complications of chemo and radiation therapy in laboratory animal models, predominantly effects on heart, blood, and bone. Recently, I am collaborating on some human studies that branch off from the laboratory animal.