Infectious disease - Drug Resistance

Researchers

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Connie Gebhart

Main focus is diagnostic bacteriology and development/evaluation of diagnostic tests. Research involves enteric diseases of animals caused by bacteria, especially Lawsonia, Brachyspira, and Campylobacter species.

 

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Dick Isaacson 

My laboratory is studying the molecular basis of pathogenesis of two pathogens: Escherichia coli and Salmonella enterica serovar Typhimurium. A common theme in each project is the identification of unique genes required for pathogenesis, understanding the functions of those genes, and determining the mechanisms controlling their expression.   

 

 

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Yinduo Ji

Dr. Ji's laboratory is interested in the functional genomics and molecular pathogenesis of a serious human and animal pathogen, Staphylococcus aureus, and antibacterial drug discovery. Specifically, we focus on different two-component signal transduction regulatory systems and several functional unknown essential proteins. Current efforts include determination of function of critical unknown genes and regulons for bacterial growth, multidrug resistance and pathogenesis, and identification of host cell signaling pathways associated with pathogenicity during host-pathogen interaction.

 

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Tim Johnson

I have two primary research areas: 1) understanding the mechanisms of plasmid dissemination associated with antibiotic resistance in bacterial pathogens; and 2) understanding the succession of the microbial communities in the animal gastrointestinal tract related to health and development. I work primarily with multidrug resistance-encoding plasmids of E. coli and Salmonella humans and production animals. The goal of this work is to understand the spread of these plasmids within and between human and animal bacterial populations. I also work closely with the poultry industries to study the bacterial populations inhabiting the gastrointestinal tracts of turkeys and chickens. The goal of this work is to understand the succession of bacterial communities over time, and how the modulation of these communities can be achieved using non-antibiotic alternatives.

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Fernando Sampedro

Risk analysis of food safety and animal health issues Antibiotic resistance of foodborne pathogens

 

 

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Randall Singer 

I seek to identify cost-effective and efficacious interventions for reducing foodborne pathogen contamination of meat and for minimizing the development and spread of antibiotic resistance in bacteria.

 

 

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