Musculoskeletal

Musculoskeletal

Researchers

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Jaime Modiano

Genetics/molecular biology of cancer - understanding heritable risk traits for common canine tumors Cancer immunology/immunotherapy - understanding mechanisms of immune response to cancer in lab, in clinic, back to lab. Current work specifically studying tumor immunosuppressive barrier Lymphocyte activation - intrinsic negative regulation and its role in maintaining lymphocyte quiescence Cancer pathology/diagnostic medicine - stratification of molecular tumor subtypes that are clinically relevant (prognostic and to guide therapy) Pre-clinical (lab animals and spontaneous tumors of dogs) drug development studies for cancer therapeutics (drugs and biologics). Development of FasL gene-based immunotherapy, ligand targeted toxins, antibodies, genetically modified bacterial vectors, targeted nanoparticles carrying gene therapy, small molecules Nicotine immunotoxicology - role of nicotine in lymphocyte activation and in tumro progression

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Al Beitz

Work in the area of pain and analgesia focusing on inflammatory psin and cancer pain. Examining mechanisms of chronic pain and mechanisms of acupuncture's effects on pain, inflammattion and cancer growth.

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Troy Trumble

Dr. Trumble in collaboration with Dr. Murray Brown at the University of Florida, established the Collaborative and Comparative Orthopedic Biomarker Research lab that focuses on the use of direct and indirect biomarkers of osteoarthritis in horses. The goal of this collaborative effort is to be able to use biomarkers to diagnose osteoarthritis in its early stages when treatment may have an effect and possibly prevent further progression in both horses and humans.

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Gerard Cramer 

My research program focuses on providing evidence based therapeutic and preventative solutions for dairy cow lameness.

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Alice A. Larson

Our focus is on pain, especially musculoskeletal pain, and depression. We're interested in the role stress hormones, mast cells and TRPV1 receptors play in these two areas.

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James E. Collins

Anatomic pathology as it relates to infectious diseases, agriculture, public health and biomedical research

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Liz Pluhar

I am currently running 3 clinical trials in dogs with brain tumors looking at novel therapies that may translate to human medicine. I also am developing a new model of a chronic critical size defect in goat tibias also to be used the large animal model used to test and compare novel bone regenerative therapies for translation into human orthopedic disease. I am also using a swine model to test treatment of traumatic brain injury and a sheep model of osteoporosis to examine the effects of PTH.

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Molly McCue

Our research focuses on the genetic basis and functional analysis of naturally occurring neuromuscular and metabolic disease in horses. Our work includes both diseases that are both clinically and economically important in the horse, as well as the use of the horse as a biomedical model.

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Jim Mickelson

I am a major contributor to the international equine genome mapping effort and study the molecular and genetic basis of metabolic, neuromuscular and musculoskeletal disease in dogs and horses. I also collaborate on the identification of genomic signatures of selection for performance traits and the functional underlying alleles in the horse.

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Cathy S. Carlson

Morphological and MRI studies of osteoarthritis and osteochondrosis.

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Jianming Wu

Main research interests are in immunogenetics and inflammation. Current active research projects are as follows: 1) Human IgG Fc receptor function in sarcoidosis; 2) Genetic mechanisms of human nutrophil antigen systems in transfusion medicine; and 3) Genetics of human chronic inflammatory diseases.

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Stephanie Valberg

The genetic and nutritional basis for equine neurologic and muscle disorders including Shivers, rhabdomyolysis and other myopathies.

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Andre F. Ziegler

Current focus is applied research of production poultry diseases.

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Michael Conzemius

 

Centers and Labs

Canine

Equine

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  • Last modified on January 24, 2014