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  Home > Swine Diseases > Mycoplasma


Mycoplasma Research at the UMN (Areas of research focus, accomplishments and highlights)


• Early detection of Mycoplasma hyopneumoniae:
     o Comparison of current methods
     o Development of new assays
• Development of an isothermal amplification method for detection of Mycoplasma hyopneumoniae
• Improving the serological detection of swine Mycoplasmas
• Development and validation of a quantitative PCR for the detection of Mycoplasma hyorhinis in clinical samples
• Development of a molecular based typing method for Mycoplasma hyorhinis


• Neonatal immune response to Mycoplasma hyopneumoniae infection and/or vaccination
• Effect of extended lactation on piglet immune response

Epidemiology and Control

• Investigating the genetic variability of Mycoplasma hyopneumoniae strains circulating in US herds
• Assessment of duration of Mycoplasma hyopneumoniae infection in infected populations
• Investigating factors affecting Mycoplasma hyopneumoniae persistence and transmission during the chronic phase of infection
• Evaluation of Mycoplasma hyopneumoniae transmission from asymptomatic carriers to unvaccinated and vaccinated pigs
• Managing gilt introduction to Mycoplasma hyopneumoniae positive herds
• Effect of sow and piglet medication on piglet colonization with Mycoplasma hyopneumoniae
• Characterization of Mycoplasma hyorhinis transmission and spread within endemically infected populations

Selected Peer-Reviewed Publications:

* Schachtschneider, K. M., Yeoman, C. J., Isaacson, R. E., White, B. A., Schook, L. B., & Pieters, M. (2013). Modulation of Systemic Immune Responses through Commensal Gastrointestinal Microbiota. PloS one, 8(1), e53969.

*Bandrick, M., Pieters, M., Pijoan, C., Baidoo, S. K., & Molitor, T. W. (2011). Effect of cross-fostering on transfer of maternal immunity to Mycoplasma hyopneumoniae to piglets. Veterinary record, 168(4), 100-100.

*Otake S, Dee S, Corzo C, Oliveira S, Deen J. Long-distance airborne transport of infectious PRRSV and Mycoplasma hyopneumoniae from a swine population infected with multiple viral variants. Vet Microbiol. 2010 Oct 26;145(3-4):198-208. Epub 2010 Mar 31. PubMed PMID: 20418029.

*Pieters M, Fano E, Pijoan C, Dee S. An experimental model to evaluate Mycoplasma hyopneumoniae transmission from asymptomatic carriers to unvaccinated and vaccinated sentinel pigs. Can J Vet Res. 2010 Apr;74(2):157-60. PubMed PMID: 20592848; PubMed Central PMCID: PMC2851728.

*Dee S, Otake S, Oliveira S, Deen J. Evidence of long distance airborne transport of porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. Vet Res. 2009 Jul-Aug;40(4):39. Epub 2009 Apr 21. PubMed PMID: 19379664; PubMed Central PMCID: PMC2701181.

* Sibila, M., Pieters, M., Molitor, T., Maes, D., Haesebrouck, F., & Segalés, J. (2009). Current perspectives on the diagnosis and epidemiology of Mycoplasma hyopneumoniae infection. The Veterinary Journal, 181(3), 221-231.

*Pieters M, Pijoan C, Fano E, Dee S. An assessment of the duration of Mycoplasma hyopneumoniae infection in an experimentally infected population of pigs. Vet Microbiol. 2009 Mar 2;134(3-4):261-6. Epub 2008 Aug 23. PubMed PMID: 18835112.

* Maes, D., Segales, J., Meyns, T., Sibila, M., Pieters, M., & Haesebrouck, F. (2008). Control of Mycoplasma hyopneumoniae infections in pigs. Veterinary microbiology, 126(4), 297-309.

* Bandrick, M., Pieters, M., Pijoan, C., & Molitor, T. W. (2008). Passive transfer of maternal Mycoplasma hyopneumoniae-specific cellular immunity to piglets. Clinical and Vaccine Immunology, 15(3), 540-543.

*Fano E, Pijoan C, Dee S. Infection dynamics of porcine reproductive and respiratory syndrome virus in a continuous-flow population of pigs also infected with Mycoplasma hyopneumoniae. Vet Rec. 2007 Oct 13;161(15):515-20. PubMed PMID: 17938409.

*Fano E, Pijoan C, Dee S, Deen J. Effect of Mycoplasma hyopneumoniae colonization at weaning on disease severity in growing pigs. Can J Vet Res. 2007 Jul;71(3):195-200. PubMed PMID: 17695594; PubMed Central PMCID: PMC1899865.

*Cardona AC, Pijoan C, Dee SA. Assessing Mycoplasma hyopneumoniae aerosol movement at several distances. Vet Rec. 2005 Jan 15;156(3):91-2. PubMed PMID: 15689041.

*Fano E, Pijoan C, Dee S. Dynamics and persistence of Mycoplasma hyopneumoniae infection in pigs. Can J Vet Res. 2005 Jul;69(3):223-8. PubMed PMID: 16187553; PubMed Central PMCID: PMC1176302.

*Fano E, Pijoan C, Dee S. Evaluation of the aerosol transmission of a mixed infection of Mycoplasma hyopneumoniae and porcine reproductive and respiratory syndrome virus. Vet Rec. 2005 Jul 23;157(4):105-8. PubMed PMID: 16040942.

*Batista L, Pijoan C, Ruiz A, Utrera V, Dee S. Assessment of transmission of Mycoplasma hyopneumoniae by personnel. J Swine Health Prod. 2004; 12(2):75-77.

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