Meet the VMED Students

Graduate Students in Veterinary Medicine

MS and PhD students in VMED are engaged in research related to animal and human health and welfare. Our students study infectious and zoonotic diseases, the development of novel treatments for cancer and other diseases, genetic research and therapies, virology and bacteriology, and ecosystem and wildlife health, among other areas of research.

    Carmen Alonso VMED

    Alonso, Carmen

    alons015@umn.edu

    Degrees
    M.S. Veterinary Medicine, University of Minnesota, 2012
    D.V.M., Universidad Complutense Madrid, 2003

    Advisers
    Dr. Peter Davies & Dr. Montserrat Torremorell

    Research
    My research focuses on the characterization of particle size ranges that are associated with airborne viruses in swine aerosols, under controlled and field conditions, to better understand the mechanisms of disease transmission within and between farms

    Publications
    Alonso, C; Goede, DP; Morrison. RB; Davies, PR; Marthaler, DG; Torremorell, M; Evidence of long-distance transport and infectivity of airborne porcine epidemic diarrhea virus. Vet Res. (2014)July 14, 45(1):73

    Alonso, C; Davies, P.R; Polson, D. D; Dee, S. A; Lazarus, W. F. Financial implications of air filtration systems for preventing PRRSV infection in large sow herds. Prev Vet Med. (2013) Sep 1;111(3-4):268-77

    Alonso, C; Murtaugh, M. P; Dee, S. A; Davies, P.R .Epidemiological study of air filtration systems for preventing for preventing PRRSV infection in large sow herds. Prev Vet Med. (2013) Oct 1;112(1-2):109-17

    Alonso C, Otake S, Davies P, Dee S. An evaluation of interventions for reducing the risk of PRRSV introduction to filtered farms via retrograde air movement through idle fans. Vet. Microbiol. (2012), 157, 3-4, 304-10

    Presentations (selected)
    Alonso C, Raynor P, Davies P, Torremorell M. Effect of the electrostatic particle ionization technology on PRRSV and influenza aerosols under experimental conditions. American Association of Swine Veterinarians Conference. Dallas, Texas, USA; 2014

    Alonso C, Raynor P, Davies P, Torremorell M. Electrostatic Particle Ionization (EPI) system as a means to decrease artificially generated PRRSV aerosols. International PRRSV Symposium. Chicago, Illinois, USA; 2013

    Alonso C, Raynor P, Davies P, Torremorell M. Preliminary data on the effect of electrostatic particle ionization system on decreasing  infectious aerosols. Allen D. Leman Swine Conference-Carlos Pijoan SDEC Symposium: Scientific Challenges and Approaches to Regional Disease Control. St. Paul, Minnesota, USA; 2013

    Alonso C, Dee S, Polson D, Davies P. Phylogenetic evaluation of historic PRRSV isolates from air filtered sow herds in North America. American Association of Swine Veterinarians Conference. San Diego, California, USA; p. 65, 2013 

    Alonso C, Dee S, Davies P. Payback period for air filtration systems in large sow herds targeting the prevention of PRRSV entry- Partial budget analysis. Allen D. Leman Swine Conference-Carlos Pijoan SDEC Symposium: Managing filtered farms. St. Paul, Minnesota, USA; 2012

    Alonso C, Dee S, Davies P. Epidemiological evaluation of air filtration in large sow herds in North America. International Symposium on Veterinary Epidemiology and Economics-ISVEE. Maastricht, Netherlands; p. 86, 2012

    Alonso C, Dee S, Davies P, Lazarus W. Economic evaluation of air filtration systems for PRRSV in large sow herds in a swine dense region in North America. International Pig Veterinary Society Congress-IPVS. Jeju Island, South Korea; Volume 2, p. 994, 2012

    Awards
     

    University of Minnesota Doctoral Dissertation Fellowship, 2015-2016

    Best Student Oral Presentation, 2015 ISERPD Symposium, Kyoto, Japan (July 2015)

    Carlos Pijoan Scholarship. CVM, University of Minnesota (January 2014)

    University of Minnesota Distinguished Master's Thesis Award. College of Veterinary Medicine University of Minnesota (October 2013)

    OGP Graduate Education Travel Award.  College of Veterinary Medicine University of Minnesota (April 2013)

    Awarded poster. Allen D. Leman Swine Conference. Economic evaluation of air filtration systems for PRRSV in large sow herds in North America (September 2012)

    1st Prize Oral. Biosafety and Biosecurity Award from the Animal Health Institute-Joseph J. Garbarino Foundation. Conference of Research Workers in Animal Diseases 2011. An evaluation of interventions for reducing the risk of PRRSV introduction to filtered farms via retrograde air movement through idle fans (back-drafting) (December 2011) 


     

    Sam Beeson VMED

    Beeson, Samantha

    beeso018@umn.edu

    Degree
    B.S., Animal Science, University of Minnesota, 2012

    Adviser
    Dr. Molly McCue

    Research
    I like horses!

    Irene Bueno VMED

    Bueno Padilla, Irene

    bueno004@umn.edu

    Degrees
    M.P.H. University of Minnesota, 2013
    D.V.M., University of Cordoba, Spain, 2007

    Adviser
    Dr. Dominic Travis & Dr. Randall Singer

    Research
    I am interested in ecosystem health research-specifically the disease dynamics at the interface between wildlife, humans and the environment.

    Publications
    Bueno Padilla, I; Klauss, G; Gardiner, C.H; Wuenschmann, A. Disseminated mite infection with ocular involvement in a juvenile bald eagle (Haliaeetus leucocephalus). Veter. Ophthalmol. J. 15(4): 271-275. 2012.

    Rutkiewicz, J; Nam, D; Cooley, T; Neumann, K; Bueno Padilla, I; Route, W; Strom, S; Basu, N. ‘Mercury exposure and neurochemical impacts in bald eagles across several Great Lakes states’. Ecotoxicol. July 2011.

    Bueno-Padilla, I; Arent, L; Ponder, J. ‘Tips for Raptor Bandaging’. Exotic DVM, Volume 12, Issue 3. 2010.

    Willette, M; Ponder, J; Cruz, L; Arent L; Bueno, I; Nicolas, O; Redig,P. ‘Management of Select Bacterial and Parasitic Conditions of Raptors’. Veter. Clinics N. Amer.- Exotic Animal Practice. September 2009.

    Presentations (selected)
    Bueno, I.; Redig, PT.; Ponder, J.; Willette, M. Bullets and bald eagles: Developing a model for dealing with conflicts in ecosystem health. The Wildlife Society, Milwaukee, WI. October 6th 2013.

    Bueno-Padilla, I.; Redig, P.T.; Willette, M.; Ponder, J. Socio-economical and political aspects of spent lead ammunition. Wildlife Disease Association. Knoxville, Tennessee. July 2013.

    Bueno-Padilla, I.; Smith, K.; Travis, D.; Machalaba, C.; Karesh, W.B. A tool to assess the public health risks of wildlife importation into the United States: The case of rodents from Latin America. Wildlife Disease Association. Knoxville, Tennessee. July 2013.

    Bueno, I. Treatment of lead intoxication in raptors. National Wildlife Rehabilitation Association Symposium. Baton Rouge, LA. March 2012.

    Bueno, I. Raptor Tissue Sampling and Necropsy. Raptor Research Foundation Conference. Duluth, Minnesota. October 2011.

    Awards
    Consortium on Law and Values in Health, Environment and the Life Sciences Fellowship, 2015

     

    Rachael Ceballos VMED

    Ceballos, Rachael

    cebal016@umn.edu

    Degree
    B.S., Biochemistry and Animal Science, Berry College

    Adviser
    Dr. Carol Cardona

    Research
    My research interest is viral disease pathogenesis with a focus on influenza A viruses. My current research is directed toward the stability of the viral envelope under varying environmental conditions. I am interested in the viral and host factors that determine transmissibility of influenza A viruses in poultry species.

    Awards
    NIFA Fellowship in Food Animal Biosecurity: Infectious Disease Ecology, 2013-2016
     

    Fabian Chamba VMED

    Chamba, Fabian

    chamb376@umn.edu

    Degree
    D.V.M., Universidad Central de Ecuador

    Advisers
    Dr. Srinand Sreevatsan & Dr. Montserrat Torremorell

    Research
    My research interest seeks to understand the effect of control measures like vaccination over genetic and antigenic evolution and variation of Influenza A virus in pig populations, especially in breeding herds.

     

    Elizabeth Coppelman VMED

    Coppelman, Elizabeth

    coppe017@umn.edu

    Degrees
    D.V.M., The Ohio State University, 2013
    B.S., Animal Sciences, with specialization in animal biology, University of Florida, 2009

    Adviser
    Dr. Troy Trumble

    Research
    My research explores the use of biomakers in the synovial fluid of the tibiotarsal joint to determine the severity of osteoarthritis (OA) in the distal intertarsal (DIT) and tarsometatarsal (TMT) joints of horses. Currently, the most accurate method of identifying OA in these joints is a combination of thorough physical, lameness, and radiographic examinations. Molecular biomarkers of OA reflect quantitative and dynamic variations associated with joint metabolism. The specific aims are to: (1) define the direct and indirect biomarker concentrations in synovial fluid, and (2) validate/refute that the biomarker concentrations in these joints increase with severity of OA in the distal joints.

    Awards
    The Ohio State University’s research grant for a project titled “Pregnancy Diagnosis before the Collection and Transfer of Horse Embryos”

    Albert Schweitzer Fellowship Award, 2011.
     

     

    Andres Diaz VMED

    Diaz, Carlos Andres

    diazj002@umn.edu

    Degrees
    M.S., National University of Colombia, 2010
    D.V.M., National University of Colombia, 2005

    Adviser
    Dr. Montserrat Torremorell

    Research
    My research is focused on the diversity and evolution of Influenza A viruses in pig populations. Influenza A is a main cause of respiratory disease in pigs and a public health threat. I use next-generation sequencing technologies to reconstruct the viral population and understand the genetic factors that allow the virus to persist in swine populations for prolonged periods of time.

    Publications
    Diaz A. Enomoto S. Romagosa A. Sreevatsan S. Nelson M. Culhane M. Torremorell M. Genome plasticity of a triple reassortant H1N1 influenza A virus during infection of vaccinated pigs. Submitted for publication.

    Diaz A. Allerson M. Culhane M. Sreevatsan S. Torremorell M. Antigenic drift of H1N1 influenza virus in pig with and without passive immunity. Influenza and Other Respir Viruses 2013 dec: 7 Suppl 4:52-60 doi: 10.1111/irv.12190.

    Torremorell M, Allerson M, Corzo C, Diaz A, Gramer M. Transmission of influenza A virus in pigs. Transbound Emerg Dis. 2012; 59:68-84 .
    Diaz A. Rodriguez N. Vera V. Ramirez G. Casas G. Mogollon D. Characterization of pig farms in the main swine producing regions of Colombia. Rev Colomb Cienc Pecu 2011;24:131-144

    Diaz A. Jaime J. Vera V. Rodriguez N. Casas GA. Mogollon JD. Postweaning multisystemic wasting syndrome: epidemiological issues. Rev Med Vet  Zoot
    2008; 55:100-114

    Presentations (selected)
    Diaz A. Corzo C. Culhane M. Sreevatsan S. Torremorell. M. Co-circulation of influenza A viruses in swine populations. Allen D. Leman Swine Conference. Saint Paul,MN, USA 2014

    Diaz A. Torremorel M. Culhane M. Sreevatsan S. Complete genome characterization of influenza A virus in sow herds. MISM Influenza workshop. Fogarty International Center. NIH. Bethesda, MD. 2014

    Diaz A. Swine Influenza A virus. V national Symposium on virology. I Latin-American congress on virology. Pontificia Universidad Javeriana Bogota, Colombia 2013.

    Diaz A. S. Enomoto. Corzo C. Culhane M. Sreevatsan S. Torremorell M. Influenza A virus infection and diversity in commercial pig herds. AASV Meeting Dallas, TX 2014

    Diaz A. Enomoto S. Culhane M. Sreevatsan S. Torremorell M. Use of NGS to study within-host and between host diversity of influenza. USDA-NIH MISMS WORKSHOP. USDA NATIONAL Centers for animal health, Ames, IA 2013.

    Diaz A. Torremorell M. Influenza infection in the sow herd. Allen D. Leman Swine Conference.  Saint Paul MN, USA, 2012.

    Diaz A. Enomoto S. Sreevatsan S. Gramer M. Torremorell M. Full genome of swine influenza A virus subtype H1N1 using next generation sequencing. IPVS.  Jeju, South Korea 2012.

    Awards
    University of Minnesota Doctoral Dissertation Fellowship, 2014-2015

    Scholarship to attend the 19th summer institute in statistical Genetics. Module 9 and 14 University of Washington. 2014

    Scholarship to attend the 6th Summer Institute in Statistics and Modeling in Infectious Diseases. Module 14. University of Washington, 2014

    MnDrive student fellowship. MnDrive Global food supply initiative. 2013-2014

    CVM student travel award. University of Minnesota, 2014

    Veterinary medicine graduate students’ representative to the Program Advisory Committee, 2013

    Vaughn Larson Award. CVM, University of Minnesota, 2013

    Carlos Pijoan scholarship. CVM, University of Minnesota, 2012

    CVM student travel award. University of Minnesota, 2012

    Caldas scholarship. Colombian Government. 2010 

     

    Sian Durward Akhurst VMED

    Durward-Akhurst, Sian

    durwa004@umn.edu

    Degree
    B.V.M.S., Glasgow University, 2009

    Adviser
    Dr. Stephanie Valberg

    Research
    My masters project is looking at horses with suspected immune mediated myositis, trying to identify the underlying cause and if there is a genetic link.

    Publications
    Durward-Akhurst SA, Mair TS, Boston R, Dunkel B. Comparison of two antimicrobial regimens on the prevalence of incisional infections after colic surgery. Vet Rec. 2013 Mar 16;172(11):287

    Naylor RJ, Durward-Akhurst SA. Use of the Accutrend Plus point-of-care monitor for blood triglyceride measurement in horses. Vet Rec. 2012 Mar 3;170(9):228.

     

    Dane Goede VMED

    Goede, Dane

    goed0051@umn.edu

    Degrees
    D.V.M., University of Minnesota, 2013
    B.S., Agricultural Biochemistry, Iowa State University, 2009

    Adviser
    Dr. Peter Davies

     

    Liz Goudie VMED

    Goudie, Elizabeth

    egoudied@umn.edu

    Degrees
    D.V.M., Ross University School of Veterinary Medicine, 2010
    B.S., Biology, Ursinus College, 2007

    Advisers
    Dr. Lynelle Graham & Dr. Alice Larson 

    Research
    My research focuses on pain as it relates to the brown adipose tissue in mice as well as tramadol pharmacokinetics in dogs.

    Nitipong Homwong VMED

    Homwong, NItipong

    homwo001@umn.edu

    Degree
    D.V.M., Kasetsart University, Thailand, 2005

    Adviser
    Dr. John Deen

    Research
    My research is focused on creating Bayesian epidemiologic models to describe the within-herd transmission of swine Influenza A virus (IAV) with various conditions of the swine production system. The epidemiological model can serve as a tool to bridge unconnected pieces of information obtained from several places in order to provide insights into the underlying process of the IAV transmission. With the goal of developing an effective IAV surveillance scheme, Bayesian epidemiological models are proposed to describe and predict the IVA transmission within the swine herd conditional to piglet production batching, gilt replacement, and vaccination programs.

    Publications
    Kanjanapruthipong, J., N. Homwong and N. Buatong. 2010. Effects of prepartum roughage neutral detergent fiber levels on periparturient dry matter intake, metabolism, and lactation in heat-stressed dairy cows. J. Dairy Sci. (93): 2589-2597

    Chairattanasat, C., O. Songserm, N. Homwong and N. Paraksa. 2009. Effect of Crude Extract Product from Capsicum spp. Supplementation in Sow Dies on Passive Immunity in Piglets. Agriculture Sci. J. (1):65-72

    Rukkwamsuk, T., N. Homwong, W. Bumkhuntod, P. Rohitakanee and R. Sukcharoen. 2006. Negative Energy Balance in Periparturient Diary Cows Raised in Small-Holder Farms in Kamphaengsaen District, Nakhonpathom Province. Kasetsart J. (Nat. Sci.) 40:1000-1004.

    Presentations
    “A comparison of two lameness detection methods in sows: A search for the best method” 13th KVAC: International conference on Trans-boundary Disease; Impact on ASEAN One Health, June 7-8, 2012, Khon Kaen, Thailand.

    “Estimating hiding behavior for lameness in sows,” Conference of research workers in animal diseases (CRWAD) annual meeting, December 5th, 2011, Chicago, Illinois, USA

    “A simulation models for Influenza A virus dissemination in a growing pig herd with waning immunity” Points of Pride Research Day, October 2, 2013, Minnesota, USA

    “Using discriminant analysis to estimate sow culling-decision error rate and its posterior probability based on lameness and productivity” Points of Pride Research Day, October 10, 2012, Minnesota, USA

     

    Vachira Hunprasit VMED

    Hunprasit, Vachira

    hunpr001@umn.edu

    Degree
    D.V.M., Chulalongkorn University, Thailand, 2007

    Advisers
    Dr. Jody Lulich & Dr. Carl Osborne

    Research
    My research interest is focused on epidemiology of feline struvite urolithiasis, with emphasis on the association of the host, agent and environment factors to the development of struvite urolith in cats.

     

    Kaushi Kanankege VMED

    Kanankege, Kaushi 

    kanan009@umn.edu

    Degrees
    M.S., Comparative Biomedical Science, University of Wisconsin-Madison, 2012
    Postgraduate Diploma in Applied Statistics, University of Peradeniya, Sri Lanka, 2010
    BVSc., University of Peradeniya, Sri Lanka, 2008

    Advisers
    Dr. Nicholas Phelps & Dr. Andres Perez

    Research
    My research interests are focused on the application of the geospatial analytical tools in pattern recognition, analysis of the association of the risk factors, and implementation of control measures in veterinary epidemiological studies.

    Publications
    Kalupahana RS, Kottawatta KS, Kanankege KST, van Bergen MA, Abeynayake P, Wagenaar JA. 2012. Colonization of Campylobacter in broiler chicken and laying hens reared in tropical climates with low bio-security housing. Applied Environmental Microbiology. 2013, 79(1):393. 2012 Oct 19

    Anklam KS, Kanankege, KST, Gonzales TK, Kaspar CW, Döpfer D. Rapid and Reliable Detection of Shiga Toxin-Producing Escherichia coli by Real-Time Multiplex PCR, Journal of Food Protection. Volume 75, Number 4, April 2012 , (8) 643-650

    Awards
    CMB-VMED graduate student travel award, 2015

    Travel award for the participation at “The international clinics on disease dynamics and data (ICI3D program)” held at University of Florida. 2014
     

    Blank 2 CMB VMED

    Kemper, Ann

    amkemper@umn.edu

    Degrees
    D.V.M., Iowa State University, 2012
    B.S., Physics, Creighton University, 2006

    Adviser
    Dr. Molly McCue 

    Yonghyan Kim VMED

    Kim, Yonghyan

    kimx4078@umn.edu

    Degree
    D.V.M., Konkuk University, Republic of Korea, 2010

    Adviser
    Dr. Maxim Cheeran

    Research
    My research interests are in immunology, specifically Porcine Epidemic Diarrhea virus (PEDV) related immune responses. A PEDV outbreak can have a damaging impact on the porcine industry. And this viral infection is especially localized in the GI tract. However, the immune responses correlate for protection in gut-associated lymphoid tissue (GALT) is still unknown. I am going to characterize pathogenicity and immune response of PEDV infection in pigs.

     

    Yoojin Kim VMED

    Kim, Yoojin

    ymkim@umn.edu

    Degrees
    D.V.M., Konkuk University, Republic of Korea, 2008
    B.A., Mass Communication, Ewha Women's University, Republic of Korea, 2000

    Adviser
    Dr. David Polzin & Dr. Jennifer Granick

    Research
    I am interested in acute kidney injury and chronic kidney disease in dogs and cats. My current research focuses on new renal biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin B, clusterin, and inosine to help an early detection of acute kidney injury in dogs and improve its prognosis.

     

    Amy Kinsley VMED

    Kinsley, Amy

    carr0603@umn.edu

    Degrees
    D.V.M., University of Minnesota, 2014
    B.S., Civil Engineering, University of Florida, 2006

    Advisers
    Dr. Meggan Craft & Dr. Andres Perez

    Research
    I am interested in understanding infectious disease dynamics in animal populations. My research focuses on developing a mathematical model to predict and control the spread of foot and mouth disease in swine.

    Publications
    Amy Kinsley, Roger Moon, Kirk Johnson, Michelle Carstensen, David Neitzel, Meggan Craft. Eastern equine encephalitis virus mosquito vectors in Minnesota (In Review, PLOS ONE)

    Presentations
    North Central Mosquito Control Association 9th Annual Meeting. April, 2013. Ham Lake, Minnesota. EEE Vector Surveillance in Northern Minnesota.

    116th Minnesota Veterinary Medical Association Annual Meeting (MVMA). February, 2013. Minneapolis, Minnesota. Public Heath emerging topics-Eastern Equine Encephalitis in Minnesota.

    Conference of Research Workers in Animal Diseases (CRWAD). December 2012. Chicago, Illinois: The ecology of eastern equine encephalitis virus in Minnesota.

    University of Minnesota College of Veterinary Medicine Points of Pride Research Day, October 2012. St. Paul, Minnesota: The ecology of eastern equine encephalitis virus in Minnesota.-Poster Competition-First Place Award

    Merial-NIH National Veterinary Scholars Symposium, August 2012. Fort Collins, Colorado: The ecology of eastern equine encephalitis virus in Minnesota.-Poster Competition.

    Awards
    Career Development Program Fellowship, Center of Excellence for Emerging and Zoonotic Animal Diseases, 2014

    Infectious Disease Dynamics and Data-Clinic on Dynamical Approaches to Infections Disease Data Travel Award (2014)

    College of Veterinary Medicine, University of Minnesota-International Travel Grant-Infectious Disease Risk Assessment (2013)

    University of Minnesota College of Veterinary Medicine, Quinlan-Litvak Scholarship Recipient (2013)

    College of Veterinary Medicine, University of Minnesota-Summer Scholars Recipient (2012)

    Summer Scholars Points of Pride Research Poster Award-1st Place (2012)

     

    Whitney Knauer VMED

    Knauer, Whitney

    knaue020@umn.edu

    Degrees
    V.M.D., University of Pennsylvania, 2010
    B.S., Animal Science, University of Vermont, 2006

    Adviser
    Dr. Sandra Godden

    Research
    My research focuses on the health, well-being, and behavior of the group housed, pre-weaned dairy calf. Currently, we are utilizing precision dairy technologies to investigate the relationship between sensor derived feeding, activity and temperature data and health. The goal of this work is to improve our understanding of normal calf behavior and to improve surveillance techniques that will help producers to improve calf health, performance and well-being at both the individual animal and group level.

    Awards
    NIFA Fellowship in Food Animal Biosecurity: Infectious Disease Ecology, 2013-2016
    RK Anderson Fellowship, 2013

     

    Fernando Leite VMED

    Lopes Leivas Leite, Fernando 

    lopes029@umn.edu

    Degrees
    M.S., Veterinary Microbiology and Immunobiology, Iowa State University, 2014
    D.V.M., Federal University of Santa Maria, Brazil, 2011

    Adviser
    Dr. Srinand Sreevatsan

    Research
    My research interests are in microbiology and immunology. Specifically in investigating host-pathogen interactions to understand and discover mechanisms that may allow for the development of improved vaccines and diagnostics.

    Publications
    Fernando L. Leite, Timothy A. Reinhardt, John P. Bannantine, Judith R. Stabel. Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity. Veterinary Microbiology, 175 (2-4): 275-85, February 2015.

    Marina C. Sinott, Luciana L. Dias de Castro, Fernando L. L. Leite, Tiago Gallina, Marlene T. De-Souza, Diogo F.L. Santos, Fabio P.L. Leite. Larvicidal activity of Bacillus circulans against the gastrointestinal nematode Haemonchus contortus in sheep. Journal of Helminthology, doi:10.1017/S0022149X14000844, 2014.

    Fernando L. Leite, Kevin D Stokes, Suelee Robbe-Austerman, Judith R. Stabel. Comparison of fecal DNA extraction kits for the detection of Mycobacterium avium subsp. paratuberculosis by polymerase chain reaction. Journal of Veterinary Diagnostic Investigation 25 (1): 27-34, January 2013.

    D’Avila Farias, Fernando Lopes Leivas Leite, Silvana Beutinger Marchioro, Bernardo Garziera Gasperin, Felipe Libardoni, Eduardo Kenji Masuda, Glaucia Denise Kommers, Luiz Francisco Irigoyen, Agueda Castagna de Vargas. Outbreak of Ovine Respiratory Mannheimiosis in Southern Brazil. Veterinária e Zootecnia 20(2): 255-260, June 2013.

    Jackeline K. Kirinus, Luciana Pötter, Letícia T. Gressler, Fernando L. L. Leite, Agueda P. C. Vargas. Phenotypic profile and antimicrobial susceptibility of Streptococcus equi isolated from horses in southern Brazil. Pesquisa Veterinária Brasileira 31(3):231-238, March 2011.

    Priscila M. S. Carmo, Agueda C. Vargas, Daniel R. Rissi, José C. Oliveira Filho, Felipe Pierezan, Ricardo B. Lucena, Fernando L. Leivas Leite, Claudio S. L. Barros. Outbreak of infectious bovine keratoconjunctivitis and haemonchosis causing mortality in calves. Pesquisa Veterinária Brasileira 31(5):374-378, May 2011.

    Presentations (selected)
    2014: Lopes Leivas Leite F., Reinhardt T., Bannantine J., Stabel J. Envelope Protein Complexes of Mycobacterium avium subsp. paratuberculosis and their Antigenicity. Oral Presentation. 12th International Colloquium on Paratuberculsis (ICP). Parma, Italy.

    2014: Lopes Leivas Leite F., Budziarek Eslabao L. Reinhardt T., Bannantine J., Stabel J. ZAP-70, CTLA-4 and Proximal T Cell Receptor Signaling in Cows Infected with Mycobacterium avium subsp. paratuberculosis. Poster Presentation. 12th ICP, Parma, Italy.

    2014: L. L. Leite F., Reinhardt T., Bannantine J., Stabel J. Antigenicity of Envelope Protein Complexes of Mycobacterium avium subsp. paratuberculosis and insights in to T cell responses of infected animals. Seminar. National Animal Disease Center, Ames, IA.

    2013: L. L. Leite F., Reinhardt T., Bannantine J., Stabel J. Antigenicity of Envelope Protein Complexes of Mycobacterium avium subsp. paratuberculosis. Oral Presentation. Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL.

    2012: Leite F., Stabel J. Comparison of Fecal DNA Extraction Kits for the Detection of Mycobacterium avium subsp. paratuberculosis. Poster Presentation. 11th ICP, Sydney, Australia.

    Awards
    MnDRIVE Global Food Initiative Fellowship, 2015-2016

    Helping Hand Award, International Association for Paratuberculosis, 12th International Colloquium on Paratuberculosis, Parma, Italy, 2014.

    Graduate Competition Award, Best in vitro study, awarded by the American College of Veterinary Microbiologists – ACVM, CRWAD, Chicago, IL, 2013.

    Travel Award, Iowa State University, Ames, IA, 2013

    Inducted in to the honorary society for agriculture Gamma Sigma Delta, for high academic achievement, Iowa State University, Ames, IA, 2013.

    Awarded Poster. First Meeting of the AUGM Health Committee. Santa Maria, RS, Brazil, 2010.

     

    CVMGRAD_macedo image

    Macedo, Nubia

    maced004@umn.edu

    Degrees
    M.S., Federal University of Minas Gerais, Brazil, 2006.
    D.V.M., Federal University of Minas Gerais, Brazil, 2005.

    Advisers
    Dr. Montserrat Torremorell & Dr. Albert Rovira

    Research
    My research focuses on investigating the use of antibiotics as a factor that influences Haemophilus parasuis colonization and its effect on immune response development. Currently, my interest is in evaluating whether H. parasuis colonization may elicit an immune response that will be protective and whether this response may be impaired by the use of antibiotics.

    Publications
    N. Macedo, A. Rovira, S. Oliveira, M. Torremorell. Effect of enrofloxacin on the carrier stage of Haemophilus parasuis in naturally colonized pigs. Canadian J. Veter. Res. Accepted on March 14, 2013.

    A. Olvera, S. Pina, N. Macedo, S. Oliveira, V. Aragon, A. Bensaid, 2012. Identification of potentially virulent strains of Haemophilus parasuis using a multiplex PCR for virulence-associated autotransporters (vtaA). The Veter. J. 191:213–218.

    N. Macedo, S.R. Oliveira, A.P. Lage, J.L. Santos, M.R. Araujo, R.M. Guedes, 2011. ERIC-PCR genotyping of Haemophilus parasuis isolates from Brazilian pigs. Veter. J. 188:362-364.

    N. Macedo, G.M. Alghamdi, C.J. Gebhart, R.M. Guedes, 2008. Enteropatia proliferativa em Equinos. Ciência Rural. , v.38, p.889 - 897.

    Presentations
    An experimental model to evaluate the effect of antibiotics on Haemophilus parasuis colonization and immunity, 44th American Association of Swine Veterinarians, March 2 - 5, 2013

    Evaluation of the immunogenic and protective capacity of a transmembrane protein of Haemophilus parasuis, 22nd International Pig veterinary Society Congress, June 10 - 13, 2012

    Enrofloxacin treatment affects the colonization stage of Haemophilus parasuis in weaned pigs, AASV, March 10-13, 2012

    Development and validation of an ELISA test to detect antibodies against Haemophilus parasuis, AAVLD, September 29-October 5, 2011

    Awards
    Travel award, Veterinary Medicine Graduate Student Conference Travel Award, 2013

    J. Lindsay Oaks Bacteriology Award (Best Oral presentation). 54th Annual Conference of the American Association of Veterinary Laboratory Diagnosticians (AAVLD). September 29-October 5, 2011.

    Travel award: American Association of Veterinary Laboratory Diagnosticians (AAVLD) Foundation, 2011.

    University Innovations - University of Minnesota, 2011.

     

    Nandita Mirajkar VMED Update

    Mirajkar, Nandita

    miraj001@umn.edu

    Degree
    B.V.Sc. & A.H., Bombay Veterinary College, Maharashtra Animal & Fishery Sciences University, India, 2010

    Adviser
    Dr. Connie Gebhart

    Research
    Swine Dysentery, caused by Brachyspira hyodysenteriae is a mucohemorragic diarrheal disease of grower-finisher pigs, responsible for significant economic losses globally. In addition, B. pilosicoli causes porcine intestinal spirochetosis, a chronic muco-diarrheal disease, and “B. hampsonii” causes a mucohemorrhagic diarrheal disease which is clinically indistinguishable from Swine Dysentery. My research involves validation of antimicrobial susceptibility testing techniques, their implementation for studying antimicrobial susceptibility patterns and investigation of potential resistance mechanisms of Brachyspira species. In addition, it involves molecular genotyping, phylogenetic analyses and molecular epidemiological studies to help elucidate the diversity, distribution, dissemination and potential evolutionary patterns of these pathogens.

    Presentations (selected)

    Mirajkar N.S. and Gebhart C.J. ‘Molecular epidemiology of global Brachyspira hyodysenteriae isolates’. Oral presentation, 6th International Conference on Colonic Spirochaetal Infections, Surrey, U.K., 2013.

    Mirajkar N.S. and Gebhart C.J. ‘Association of Brachyspira antibiograms with species and source’. Oral presentation, 2013 Allen D. Leman Swine Conference, Saint Paul, U.S.A., 2013.

    Mirajkar N.S. and Gebhart C.J. ‘Validation of a broth microdilution method and investigation of in vitro antimicrobial susceptibilities of porcine Brachyspira species’. Oral presentation, 56th Annual Conference of the American Association of Veterinary Laboratory Diagnosticians, San Diego, California, U.S.A., 2013.

    Mirajkar N.S., Bekele A.Z., Chander Y and Gebhart C.J. ‘Diversity and distribution of “Brachyspira hampsonii” in U.S. swine herds’. Oral presentation, 23rd International Pig Veterinary Society Congress, Cancun, Mexico, 2014.

    Mirajkar N.S., Bekele A.Z., Chander Y and Gebhart C.J. ‘Molecular characterization of emerging “Brachyspira hampsonii”, Poster presentation, 2014 Allen D. Leman Swine Conference, Saint Paul, U.S.A., 2014.

    Mirajkar N.S. and Gebhart C.J. ‘Source and species of swine Brachyspira influence antibiogram profiles’. Poster presentation, CVM Points of Pride Research Day, University of Minnesota, Saint Paul, U.S.A. 2014.

    Mirajkar N.S., Bekele A.Z., Chander Y and Gebhart C.J. ‘Diversity and distribution of a novel swine dysentery pathogen “Brachyspira hampsonii”.’ Oral presentation, 95th Conference of Research Workers in Animal Disease, Chicago, U.S.A., 2014.
     

    Publications
    Mirajkar, NS, AZ Bekele, YY Chandler, and CJ Gebhart, 2015. Molecular epidemiology of novel pathogen Brachyspira hampsonii reveals relationships between diverse genetic groups, regions, host species, and other pathogenic and commensal Brachyspira. J. Clin. Microbiol. PMID:26135863

    Mirajkar N.S. and Gebhart C.J. ‘Understanding the Molecular Epidemiology and Global Relationships of Brachyspira hyodysenteriae from Swine Herds in the United States: A Multi-Locus Sequence Typing Approach’. PLoS ONE 9(9): e107176. doi: 10.1371/journal.pone.0107176

    Mirajkar NS and Gebhart CJ ‘Identifying Dysentery Genotypes’. National Hog Farmer, Jan 2014.
     

    Awards
    Emerging and Zoonotic Diseases Graduate Fellowship 2014-2015, College of Veterinary Medicine, University of Minnesota.

    Carlos Pijoan Graduate Student Fellowship in Swine Medicine 2014-2015, College of Veterinary Medicine, University of Minnesota, U.S.A.

    MnDRIVE Global Food Supply Initiative Graduate Research Fellowship 2014-2015, University of Minnesota, U.S.A.

    Travel Award for two oral presentations at the 6th International Conference on Colonic Spirochaetal Infections in U.K., provided by the VMED program, College of Veterinary Medicine, University of Minnesota, U.S.A.

    J. Lindsay Oaks Best Student Bacteriology Award, 56th Annual Conference of the American Association of Veterinary Laboratory Diagnosticians, San Diego, U.S.A., 2013.

    Trainee travel award for the 56th Annual conference of the American Association of Veterinary Laboratory Diagnosticians, San Diego, U.S.A., 2013.

    Best poster presentation award in the Emerging and Zoonotic Diseases program at the CVM UMN Points of Pride Research Day, Saint Paul, U.S.A, 2013.

    Young scientist award at the 6th International Conference on Colonic Spirochaetal Infections, Surrey, U.K., 2013.

    AAA Scholars Abroad Program 2011 Award from the American Alumni Association, India, 2011.

    Lotus Trust Graduate studies scholarship from the Lotus Trust foundation, India, 2011.

    S.K. Patil Scholarship from the Shri Brihad Bhartiya Samaj foundation, India, 2011.

    Travel award for graduate studies abroad from the Tatachem Golden Jubilee foundation, India, 2011.

    Graduate education abroad grant from the Pirojshah Godrej foundation, India, 2011.
     

     

     

    Hadia Mohammad VMED

    Mohammad, Hadia

    moham698@umn.edu

    Degrees
    M.S., Microbiology, Zagazig University, 2010
    B.S., Pharmacy, Zagazig University, 2004

    Adviser
    Dr. Pam Skinner 

    Research
    The mucosal surfaces are critical sites of transmission of both HIV & simian immunodeficiency virus (SIV). I believe that the ability of a vaccine to induce mucosal immunity is important in order to prevent or reduce the dissemination of HIV and SIV by providing a first line of defense.  Using the SIV-infected rhesus macaque as a model for HIV infection, my research focuses on evaluating the ability of CD8 T cell-vaccines to induce high levels of functional SIV-specific CD8 T cells in genital, rectal & lymphoid tissue.  I am determining the localization, abundance, and phenotype of SIV-specific CD8 T cells in situ in genital, rectal & lymphoid tissue of vaccinated and control animals.

     

    Eugene Nwaokorie VMED

    Nwaokorie, Eugene

    nwoko006@umn.edu

    Degrees
    M.S., Veterinary Medicine, University of Minnesota, 2010
    D.V.M., University of Nigeria, Nsukka, Nigeria, 1987

    Advisers 
    Dr. Carl Osborne & Dr. Jody Lulich

    Research
    My research interests focus on the epidemiology of urolithiasis in domestic animals. As a team we have worked on the epidemiology of urolithiasis in dogs, cats and ferrets. Now we are working on the epidemiology of urolithiasis in goats.  We plan to extend this study to sheep, cows, horses, pigs, rabbits and guinea pigs. Knowledge of these risk factors may facilitate development of surveillance strategies that result in earlier detection of urolithiasis in domestic animals as well as help in the design of effective diagnostic, therapeutic and prevention of this condition.

    Publications
    Osborne CA, Albasan H, Lulich JP, Nwaokorie EE et al. Quantitative Analysis of 4468 Uroliths Retrieved from Farm Animals, Exotic Species, and Wildlife Submitted to the Minnesota Urolith Center: 1981 to 2007.  Vet Clin North Am Small Anim Pact 2009; Vol.39, Issue 1: 65-78.

    Nwaokorie EE, Osborne CA, Lulich JP, Albasan H et al. Epidemiology of struvite uroliths in ferrets 272 cases (1981-2007). J Am Vet Med Assoc 2011; 339: 1319-1324.

    Osborne CA, Ulrich LK, Nwaokorie E E. Reactive versus empathic listening: what is the difference?  J Am Vet Med Assoc 2013; 242: 460-462.

    Nwaokorie EE, Osborne CA, Lulich JP, Albasan H et al.   Epidemiological evaluation of cystine urolithiasis in domestic ferrets (Mustela putorius furo):70 cases (1992-2009) J Am Vet Med Assoc 2013; 242: 1099-1103.  

     

    Kruthikaben Patel

    Patel, Kruthikaben

    patel310@umn.edu

    Degrees
    M.V.Sc., College of Veterinary and Animal Sciences, Bikaner, Rajastthan, India, 2013
    B.V.Sc. & A.H., Rajiv Gandhi College of Veterinary and Animal Sciences, 2010

    Adviser
    Dr. Sandra Godden

    Research
    High levels of bacteria in bedding are associated with increased bacteria loads on teat ends and with an increased risk for environmental mastitis infections. Unfortunately the dairy industry needs significantly more information on the relationship between bedding bacteria counts and udder health. Also science-based cutpoints are not available to assist producers and consultants in monitoring and interpreting bedding culture reports as part of a comprehensive milk quality program. My research is about investigating the relationship between bedding bacterial counts and udder health in U.S. dairy farms and also to gain a better understanding of the many of management-related factors that may influence bedding bacterial counts and mastitis risk so that guidelines can be developed to assist producers in improving udder health and milk quality.

    Publications
    Kruthikaben D, Sharma S, Maherchandani S, Shringi BN, Kashyap SK. Antimicrobial susceptibility pattern of microbes isolated from otitis externa of dogs. J. Canine Devel. Res. 2012, 8: 47-50.

    Sharma S, Kruthikaben D, Shringi BN, Maherchandani S, Kashyap SK. Resistotyping of Escherichia coli isolated from faeces of enteritic dogs. Veterinary Practitioner. 2012, 14(1): 136-138

     

    Catalina Picasso VMED

    Picasso, Catalina

    picas001@umn.edu

    Degree
    D.V.M., Universidad de la Republica Oriental del Uruguay. Facultad de Veterinaria, 2009

    Adviser
    Dr. Andres Perez

    Research
    The goal of my MsSc thesis is to characterize the spatial and temporal dynamics of bovine tuberculosis (BT), and to assess the nature and extent of the association between epidemiological factors and BT outbreaks in Uruguay. Results will contribute to design and implement risk-based surveillance strategies for BT in Uruguay and the United States.

     

    Luiza Ribeiro VMED

    Ribeiro Roos, Luiza

    ribei028@umn.edu

    Degree
    D.V.M., Universidade de Brasilia, 2013

    Adviser
    Dr. Maria Pieters

    Research
    I'm interested in the infection dynamics of Mycoplasmas that affect the swine species. My current research focus on understanding the transmission patterns of Mycoplasma hyopneumoniae in order to develop a gilt acclimation protocol prior entering the breeding herd.

    Presentations
    Roos L.R., Fano E., Payne B., Pieters M. ‘Optimal ratio for successful exposure of gilts to Mycoplasma hyopneumoniae’. Poster presentation, CVM Points of Pride Research Day, University of Minnesota, Saint Paul, Minnesota, USA. 2014

    Roos L.R., Pieters M.' Preliminary results on a protocol for Mycoplasma hyopneumoniae gilt acclimation'. Minnesota Veterinary Medical Association Annual Meeting. Minneapolis, Minnesota, USA.
     

    Junjie Shao VMED

    Shao, Junjie

    jshao@umn.edu

    Degrees
    M.S., Pathogenic Organisms, Fudan University, 2005
    B.S., Forensic Medicine, Fudan University, 2002

    Adviser
    Dr. Yuying Liang

    Research
    I am working on the arenaviruses family, with a research focus on the interaction between viral proteins and host, and the pathogencity of the different GPC mutants of PICV.
     

    Fernanda Shoyama VMED

    Shoyama, Fernanda

    fshoyama@umn.edu

    Degree
    B.S., Biological Sciences, Federal University of Uberlandia, Brazil

    Adviser
    Dr. Srinand Sreevatsan

    Research
    My master’s project is to understand the metabolic networks of Mycobacterium avium subsp. paratuberculosis (MAP) in order to sharpen our understanding of MAP virulence and to devise optical vaccines and cultivation media to enhance its diagnosis.

    Publications
    Yaya Wang, Iftach Shaked, Stephanie M. Stanford, Wenbo Zhou, Julie M. Curtsinger, Zbigniew Mikulski, Zachary R. Shaheen, Genhong Cheng, Kristy Sawatzke, Amanda M. Campbell, Jennifer L. Auger, Hatice Bilgic, Fernanda M. Shoyama, David O. Schmeling, Henry H. Balfour Jr., Kiminori Hasegawa, Andrew C. Chan, John A. Corbett, Bryce A. Binstadt, Matthew F. Mescher, Klaus Ley, Nunzio Bottini, & Erik J. Peterson. The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity. Immunity, 2013 39(1), 111–122

    Silva, Alexandre L. Neves ; Adade, Camila M. ; Shoyama, Fernanda M. ; Neto, Cecílio Purcino S. ; Souto-Padrón, T. C. B. S. ; de Almeida, Mauro V. ; Rezende, Carlos A. de Magalhà es ; Silva, Claudio V. ; Souza, Maria A. . In vitro leishmanicidal activity of N-dodecyl-1,2-ethanediamine. Biomedicine & Pharmacotherapy, v. 66, p. 180-186, 2012. 

    Awards
    MnDRIVE Global Food Supply Initiative Fellowship, 2014-2015

     

    Grant Stoddard VMED

    Stoddard, Grant

    stodd038@umn.edu

    Degree
    B.S., Animal Science, University of Wisconsin-River Falls

    Advisers
    Dr. Gerard Cramer & Dr. Sandra Godden

    Research
    My research interests are in the dairy industry, specifically animal welfare and the hoof trimming process. This area is currently lacking strong scientific evidence for its efficacy. I am going to use random controlled trials and observational studies to investigate the effect, timing and proper technique of hoof trimming for dairy cattle. 

    Publications
    Stoddard G. C. and K. D. Vogel. 2013. Cull with care. Hoard’s Dairyman. 158(18):679. 

    Stoddard G. C. and K. D. Vogel. 2013. From farm to harvest: beef quality begins with smart culling. Hoard’s Dairyman.  158(20):745.

    Stoddard G. C. and K. D. Vogel. 2013. Cull With Care: When Culling is Not an Option. Hoard’s Dairyman. 158(21):804.

    Awards
    MnDRIVE Global Food Initiative Fellowship, 2015-2016

    RK Anderson Fellowship, 2014

    University of Wisconsin River Falls Rochelle Junkman Seymour Award, 2014

    University of Wisconsin River Falls Summa Cum Laude, 2014

     

    Jisun Sun VMED

    Sun, Jisun

    sunxx801@umn.edu

    Degrees
    M.S., Preventive Medicine, Kangwon National University, Republic of Korea, 2012
    D.V.M., Kangwon National University, Republic of Korea, 2010

    Adviser
    Dr. Peter Davies

    Research
    My research focuses on the prevalence investigation of Staphylococcus aureus including methicillin resistant Staphylococcus aureus (MRSA) in pig and swine veterinarian in U.S to evaluate colonization and infection patterns. We also have determined the predominant S.aureus genetic types using spa typing and MLST methods from isolates to understand the current distribution of this pathogen in pig industry.

    Publications
    Peter Davies, Jisun Sun, My Yang.  Evidence Suggests 'Livestock-Associated MRSA' Not Widespread in U.S. Swine Industry. National Hog Farmer. November 3, 2014

    Jisun Sun, Youngjae Cho, Jang Hyuck Han, Joo Hyun Jang, Zheng Wu Kang, Tae-Wook Hahn. An immunoproteomic approach for characterization of the outer membrane proteins of Salmonella Gallinarum. Electrophoresis. 2014 Mar;35(6):888-94

    Cho, Y, J Sun, I S Bang and Hahn T-W. 2014. Attenuated virulence and protective efficacy of a vaccine with multiple mutated Salmonella enterica serovar Typhimurium in mouse. Journal of Pure and Applied Microbiology. 8(2):1137-1143

    Kiju Kim, Dooree Kim, Jisun Sun, Soyeon Park, Youngjae Cho, Hyun-Jeong Ko, Hong-Gu Joo, Tae-Wook Hahn. Comparative evaluation of the murine immune responses to Salmonella enterica serovars Enteritidis, Gallinarum and Typhimurium infection. Korean J Vet Res. 2013 53(2) : 95-101

    Sun, J, Y Cho, J-H Jang, Z-W Kang, J-H Han and Hahn, T-W. Proteomic analysis and protective effects of outer membrane proteins from Salmonella Gallinarum in chickens. Korean Journal for Food Science of Animal Resources. 2013. 33 (2):281-6

    Jisun Sun, and Tae-Wook Hahn. Comparative proteomic analysis of Salmonella enterica serovars Enteritidis, Typhimurium and Gallinarum. J Vet Med Sci. 2012 Mar;74(3):285-91.

    SunShin Yi, Jisun Sun, Hyun-soo Kim, Shien-Young Kang and Tae-Wook Hahn. Sequence analysis and expression of ORF5 in Korean isolate of porcine reproductive and respiratory syndrome virus. Journal of Bacteriology and Virology, 2011.41(3):173-181.

    Presentations
    Jisun Sun, My Yang, Peter Davies (2015). Quantitative evaluation of nasal carriage of Staphylococcus aureus in swine veterinarians. American Association of Swine Veterinarians (AASV) 2015, Orlando Fl, USA, Feb 28-Mar 3, 2015

    Jisun Sun, My Yang, Srinand Sreevatsan, Peter Davies (2014). Longitudinal study of nasal carriage of Staphylococcus aureus in swine veterinarians and its implications for health. Conference of Research Workers in Animal Disease (CRWAD). Chicago Il, USA, Dec 7-9 2014. (Oral)

    Jisun Sun, My Yang, Srinand Sreevatsan, Peter Davies (2014). Longitudinal study of nasal carriage of Staphylococcus aureus in swine veterinarians and its implications for health.16th International Symposium on Staphylococci and Staphylococcal Infections(ISSSI). Chicago Il, USA, Aug 26-29, 2014. #234

    Jisun Sun, Leticia Linhares, My Yang, Srinand Sreevatsan, Peter Davies. 2013. The evaluation of molecular epidemiological relatedness within ST5 Staphlyococcus aureus isolated from swine veterinarians in the USA. 3rd ASM-ESCMID, Copenhagen, Denmark.

    Davies PR, Sreevatsan S, Sun J, Yang M (2013). Patterns of S.aureus and MRSA colonization and infection in US swine veterinarians. EPICOH, Utrecht, The Netherlands, Jun 18-20, 2013

    Jisun Sun, Leticia Linhares, My Yang, Srinand Sreevatsan, Peter Davies. 2013. Genetic diversity of ST5 Staphylococcus aureus isolated from swine veterinarians in the USA. Safepork2013, Maine, USA.

    Awards
    COGS fall 2013 travel award

    ASM Student Travel Grant to attend the 3rd ASM-ESCMID  Conference on Methicillin-resistant Staphylococci in Animals: Veterinary and Public Health Implications in Copenhagen, Denmark. 2013

    Office of Graduate Programs Travel Award, Fall 2013

     

    Dane Tatarniuk VMED

    Tatarniuk, Dane

    tatar014@umn.edu

    Degree
    D.V.M., University of Saskatchewan, 2011

    Adviser
    Dr. Troy Trumble

    Research
    My area of research is investigating intra-articular therapies for management of osteoarthritis in the horse, through use of measuring indirect immunologic biomarkers in synovial fluid. Specifically, my current investigation is focused on the intra-articular medication: autologous conditioned serum (more commonly known as 'IRAP').

    Awards
    2013 recipient of the American College of Veterinary Surgeons Foundation - Surgeon In-Training Grant, entitled: "Concentrations of Cytokines and Matrix Metalloproteinases in Serum and Synovial Fluid Following Injection of Autologous Conditioned Serum into Equine Osteoarthritic Distal Inter-Phalangeal Joints."

     

    CVMGRAD_tousignant

    Tousignant, Steve

    tous0026@umn.edu

    Degrees
    D.V.M., University of Minnesota, 2011
    B.S., University of Minnesota, 2008

    Adviser
    Dr. Bob Morrison

    Research
    My research focus is on the epidemiology of PRRS virus in swine herds with an interest in risk factors of infection including spatial and temporal analysis and mapping. We have worked to develop a database of 10 production companies, of approximately 300 sow herds, representing nearly 1,000,000 sows in 14 states. Using this database, we have designed field trials to understand the effect of PRRS vaccination on the frequency and variety of PRRS viruses detected in air within a region. I have also conducted several trials on the role of oral vitamin D3 supplementation in suckling and post-weaned pigs and the response in performance and immune function.

    Publications
    Tousignant S., Henry S., Rovira A., Morrison R. Effect of oral vitamin D3 supplementation on growth and serum 25-hydroxy vitamin D levels in pigs up to 7 weeks of age (under review).

    Tousignant S., Morrison R. National PRRS project provides infection rate. National Hog Farmer Online, July 2012.

    Tousignant S., Morrison R. Are you ready for PRRS season? Pork Magazine, November 2012.

    Presentations
    Tousignant S., Morrison R. (2010). A survey of anaerobic digesters on swine farms (student poster session). American Association of Swine Veterinarians, Omaha, Nebraska.

    Tousignant S., Henry S., Morrison R. (2011). A field trial to determine effect of vitamin D oral supplementation (oral presentation). Allen D. Leman Swine Conference, St. Paul, MN.

    Tousignant S., Goede D., Morrison R. (2012). Identifying areas at high risk for epidemic spread of PRRS virus (oral presentation). Allen D. Leman Swine Conference, St. Paul, MN.

    Tousignant S., Morrison R. (2012). Sow herd PRRS incidence/prevalence project (oral presentation). Allen D. Leman Swine Conference, St. Paul, MN.

    Tousignant S., Rovira A., Morrison R. (2012). Reproduction of Peri Weaning Failure to Thrive Syndrome in weaned pigs and effect of supplemental vitamin D (oral presentation). Allen D. Leman Swine Conference, St. Paul, MN.

    Grants
    Morrison R., Tousignant S. (co-investigator). Impact of pig farm density on incidence of PRRS in a cohort of sow herds. National Pork Board. Funding begins October 2012.

    Morrison R., Tousignant S. (co-investigator). A pilot study to determine risk of PRRS infection from 3 years of retrospective data as a means of predicting future outbreaks in a large sample of US sow herds. College of Veterinary Medicine, Population systems signature series grant. Funding begins October 2012.

    Awards
    National Needs Fellowship in Food Animal Biosecurity: Infectious Disease Biology. Fellowship begins January 2013.

     

    Jo Varshney VMED

    Varshney, Jyotika

    varsh005@umn.edu

    Degrees
    M.S., Pathobiology, Pennsylvania State University, 2012
    BVSc. & A.H., Anand Agricultural University, India, 2009

    Adviser
    Dr. Subbaya Subramanian & Dr. David Largaespada

    Research
    Osteosarcoma is the most common primary bone malignancy affecting children, adolescents and young adults. Additionally, osteosarcoma is commonly found in canines, with approximately 10,000 new cases each year. We have found that a unifying feature of osteosarcoma is the overexpression of miR-17-92 microRNAs. We have deciphered that deregulation of 14q32miR/cMYC network leads to overexpression of miR-17-92 in osteosarcoma. This deregulation is associated with poorer outcomes in osteosarcoma and is preserved in naturally occurring canine osteosarcoma suggesting a conserved disease mechanism. Additionally, our studies show that the prodrug Minnelide inhibits cMYC expression and downregulates miR-17-92 miRNAs. Together, our data suggests that upregulation of miR-17-92 miRNAs contributes to osteosarcoma progression and Minnelide reduces tumor burden in osteosarcoma by inhibiting miR-17-92 expression.

    Publications
    Varshney Jyotika B., Very Katherine J., Williams Jen L., Hegarty John P., Stewart David B., Lumadue Jeanne, Venkitanarayanan Kumar, and Jayarao Bhushan M.. Foodborne Pathogens and Disease. October 2014, 11(10): 822-829. doi:10.1089/fpd.2014.1790. 

    Varshney, J.; Ooi, J.H.; Jayarao, B..M.; Istvan, A.; Fisher, J.; Smith, R.; Patterson, A.; Cantorna, M.T. White button mushrooms increase microbial diversity and accelerate the resolution of Citrobacter rodentium infection in mice. The Journal of Nutrition 143, no. 4 (2013): 526-532.

    Varshney J, Subramanian S. “MicroRNAs in Cancer.” Current Science. 2013

    Varshney J and Subramanian S. “MicroRNA gene regulation in osteosarcoma, Osteosarcoma: Symptoms, Diagnosis and Treatment Options.” Nova Publications. Book chapter.

    Presentations
    Platform presentation: cMYC transactivated miR-17-92 cluster plays a crucial role in osteosarcoma progression, 2013 International Conference on Advances in Canine and Feline Genomics and Inherited Diseases. Broad Institute at MIT Cambridge, USA

    Awards
    University of Minnesota Doctoral Dissertation Fellowship, 2015-2016

    Vaughn Larson Award. CVM, University of Minnesota, 2014 

    CGE Travel Grant, August 2014

    CVM Research Day Best Poster Award, University of Minnesota, Minneapolis, MN 2013

    Anand Agricultural University: University topper and Gold Medalist (2009):
    - Highest GPA in Clinical Sciences (Surgery, Radiology, and Theriogenology)
    - Highest GPA in Para-clinical Sciences (Pathology, Microbiology and Parasitology)

     

    Fuyuan Wang VMED

    Wang, Fuyuan

    wang3044@umn.edu

    Degrees
    M.S., Pharmacology, University of Minnesota, 2013
    M.S., Toxicology, University of Michigan, 2008
    M.E., Chemical Engineering, Tsinghua University, 2006
    D.V.M., Shandong Agricultural University, 2001

    Adviser
    Dr. Sabita Roy

    Research
    Alteration in gut microbiome has been shown to contribute to bowel dysfunction and gut barrier disruption. We have recently demonstrated that morphine treatment results in significant disruption in gut barrier function leading to increased translocation of gut commensal bacteria. Gut microbiome plays an important role in maintaining gut homeostasis. However, the effect of morphine on gut microbiome has not been investigated. Citrobacter rodentium is a natural mouse pathogen that models intestinal infection by enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) in humans and causes attaching and effacing (A/E) lesions and colonic hyperplasia. My research focuses on the effects of morphine treatment on host mucosal immunity, gut microbiota, and bacterial virulence in a Citrobacter rodentium-mouse model. My research will expand understanding of effects of morphine on the microbiome-neuroimmune axis, and of its role in the gut homeostasis.

    Publications 
    Zhan Y, Chen PJ, Sadler WD, Wang F, Poe SA, Eaton KA, Nunez G, Chen G. Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury. Cancer Research. 2013, 73(24):7199-210.

    He X, Lyons DM, Toffaletti DL, Wang F, Qiu Y, Davis MJ, Meister DL, Dayrit JK, Lee A, Osterholzer JJ, Perfect JR, Olszewski MA. Virulence Factors Identified by Cryptococcus neoformans Mutant Screen Differentially Modulate Lung Immune Responses and Brain Dissemination. Am J Pathol. 2012, 181(4):1356-1366

    Qiu Y, Zeltzer S, Zhang Y, Wang F, Chen GH, Dayrit J, Murdock BJ, Bhan U, Toews GB, Osterholzer JJ, Standiford TJ, Olszewski MA. Early Induction of CCL7 Downstream of TLR9 Signaling Promotes the Development of Robust Immunity to Cryptococcal Infection. Journal of Immunology. 2012, 188(8):3940-3948

    Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. Journal of Immunology. 2011, 186(12):7187-7194.

    Zhang Y, Wang F, Bhan U, Huffnagle GB, Toews GB, Standiford TJ, Olszewski MA. TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans infected lungs. Am J of Pathol. 2010, 177(2):754-765. (co-first author)

    Zhang Y, Wang F, Tompkins KC, McNamara A, Jain AV, Moore BB, Toews GB, Huffnagle GB, Olszewski MA. Robust Th1- and Th17-Immunity Supports Pulmonary Clearance but Cannot Prevent Systemic Dissemination of Highly Virulent Cryptococcus neoformans H99. Am J of Pathol. 2009, 175(6):2489-2500.

    Wang F, Miao C, Liu Z. Effect of Electric Field on Cell Growth, Permeability, and Extracellular Enzymatic Activity of Phanerochaete chrysosporium, Chinese Journal of Process Engineering. 2007, 07(02): 86-90.

    Wang F, Diao Y. Isolation and Identification of Avian Escherichia coli from Chickens in Partial Regions of Shandong Province, Shandong Journal of Animal Science and Veterinary Medicine. 2002, 15(1):1-2.

    Presentations (Selected)
    Wang F, Sindberg G, Banerjee S, Ma J, Li D, Johnson T, Roy S. Morphine treatment shifts the mouse colonic microbiome and promotes systemic dissemination of Citrobacter rodentium. 20th Scientific Conference of Society on NeuroImmune Pharmacology (SNIP), New Orleans, Louisiana, March 26-29, 2014

    Wang F, Meng J, Roy S. Morphine Treatment Increases Citrobacter rodentium Virulence and Disrupts Infection Induced IL17a Immune Response in Mice. The 16th International Congress of Mucosal Immunology (ICMI 2013), Vancouver, BC, Canada, July 2013

    Liu M, Wang F, Shaw M, Nunez G, Chen GY. Nod1 functions in T cells to suppress inflammation-associated colorectal cancer. Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research, Chicago, IL. Mar 31-Apr 4, 2012. Cancer Res 2012;72(8 Suppl):Abstract nr 532. doi:1538-7445.AM2012-532

    Awards
    Early Career Investigator Travel Award, Society on NeuroImmune Pharmacology (SNIP), 2014

    Office of Graduate Programs Enhanced Learning Travel Award, 2013

     

    Sylvia Wanzala VMED

    Wanzala, Sylvia

    wanza003@umn.edu

    Degrees
    M.Sc., Molecular Biology & Biotechnology, Makerere University, 2013
    D.V.M., Makerere University, 2005

    Adviser
    Dr. Srinand Sreevatsan

    Research
    My research will involve the comprehensive tracking of biomarkers for diagnostics and One Health. I will be working on zoonotic TB in humans and animals as well as testing the efficacy of a novel diagnostic tool on samples from these populations (wildlife, cattle and humans).

    Awards
    MnDRIVE Global Food Initiative Fellowship, 2015-2016

    ICI3D Clinic on Dynamical Approaches to Infectious Disease Data travel award, 2014

    Fogarty Global Health Fellowship, 2012-2013

     

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