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  Home > VBS Faculty > Randall Singer

Randall Singer

VBS Faculty Singer Randy

e-mail: singe024@umn.edu

300A Veterinary Science
1971 Commonwealth Avenue
University of Minnesota
St. Paul, MN 55108
B.A., University of California, San Diego
D.V.M., University of California, Davis
M.P.V.M., University of California, Davis
Ph.D., University of California, Davis

Research Interests
My research is focused in infectious disease epidemiology. I apply an ecological approach to a disease system, wherein host, environment, agent and other factors that influence pathogen transmission and persistence are evaluated. Within this framework, I have investigated food-borne pathogens, vector-borne pathogens, and the spread of antimicrobial resistance genes among bacteria. These studies incorporate tools and methods in a variety of areas, including molecular biology, microbiology and mathematical modeling. One major area of research in my laboratory is the investigation of the ways in which various selection pressures influence the dissemination and persistence of antimicrobial resistance genes.  We have developed mathematical models to predict how changes in these selection pressures, including changes in agricultural management strategies, will affect the stability of antimicrobial resistance genes in bacterial populations. Ultimately, our multidisciplinary team will combine epidemiological, ecological, microbiological and hydrological models to predict the likelihood and extent of ecosystem-human-animal transmission of specific bacteria and bacterial genes.



Selected Publications
(For a comprehensive list of  Dr. Singer's recent publications, refer to PubMed, a service provided by the National Library of Medicine.)

Singer, R.S., M.P. Ward, and G. Maldonado. 2006. Can landscape ecology untangle the complexity of antibiotic resistance? Nature Reviews Microbiology. 4:943-952.

Singer, R.S., L.A. Cox, J.S. Dickson, H.S. Hurd, I. Phillips, and G.Y. Miller. 2007. Improved food animal health decreases human foodborne illness.  Preventive Veterinary Medicine. 79:186-203.

Muñoz-Aguayo, J., K.S. Lang, T.M. LaPara, G. González, and R.S. Singer. 2007. Evaluating the effects of chlortetracycline on bacteria in a simulated river water ecosystem.  Applied and Environmental Microbiology. 73:5421-5425.

Boyer, T.C., M.P. Ward, R.L. Wallace, and R.S. Singer. 2008. Regional seroprevalence of bluetongue virus in Illinois and Indiana cattle.  American Journal of Veterinary Research. 68:1212-1219.

Boyer, T.C., M.P. Ward, R.L. Wallace, E. Zhou, and R.S. Singer. 2008. Exploratory spatial data analysis of regional seroprevalence of epizootic hemorrhagic disease virus in Illinois and Indiana cattle.  American Journal of Veterinary Research. 69:1286-1293.

Singer, R.S., S.K. Patterson, and R.L. Wallace. 2008. Effects of therapeutic ceftiofur administration in dairy cattle on Escherichia coli dynamics in the intestinal tract.  Applied and Environmental Microbiology. 74:6956-6962.

Singer, R.S., A.E. Mayer, T.E. Hanson, and R.E. Isaacson. 2009. Do microbial interactions and cultivation media decrease the accuracy of Salmonella surveillance systems and outbreak investigations?  Journal of Food Protection. 72:707-713.

Call, D.R., R.S. Singer, D. Meng, S.L. Broschat, L.H. Orfe, J.M. Anderson, D.R. Herndon, L.S. Kappmeyer, J.B. Daniels, T.E. Besser. 2010. BlaCMY-2 positive Inc A/C plasmids from Escherichia coli and Salmonella enterica are a distinct component of a larger lineage of plasmids.  Antimicrobial Agents and Chemotherapy. 54:590-596. 

Current Funding
“Food Safety, Food Production and the Global Food Supply,” NRICGP-USDA.

“Modeling Sampling Strategies for Detecting Intentional Contamination of Imported Food Systems,” NCFPD.

Honors and Awards
Presidential Early Career Award for Scientists and Engineers. 2000.

McKnight Land-Grant Professor, University of Minnesota, 2005-2007.

Invited Member, U.S. Delegation to the Codex Alimentarius Intergovernmental Task Force on Antimicrobial Resistance, 2007 – 2010.

Resident Fellow, Institute on the Environment, University of Minnesota, 2009-2011.




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