Leslie Sharkey

Shark009@umn.edu

Degrees

B.S. with Honors, University of Michigan 1987
D.V.M. Ohio State University 1993
Ph.D. Ohio State University 1998

Diplomate American College of Veterinary Pathologists (Clinical Pathology)

Research Interests

My research interests include assessing risk factors for the development of long-term cardiovascular complications to cancer chemotherapy, with an emphasis on modeling the effects of gender and genetic background. I am also interested cancer biology, with an emphasis on the role of the tumor microenvironment and tumor interactions with normal tissues in the progression of disease. I am interested in a comparative medicine approach utilizing spontaneous and genetic models when possible.

Clinical Interests

My main clinical interests are improving the diagnostic accuracy of cytology and optimization of the use of clinical chemistry testing as a diagnostic tool.

Instructional areas

I teach cardiovascular pathology and clinical pathology in the veterinary curriculum. My goals are to encourage critical thinking in the diagnostic evaluation of clinical pathology data using a case-based approach. In addition, I try to foster critical thinking in the evaluation of new diagnostic tests and methods.

Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

Current Funding

• “Whole-body MRI bone marrow staging of canine lymphoma: a potential animal model” University of Minnesota Academic Health Center Seed grant, Co-investigator, $25,000
• “Genetic Background and the Angiogenic Phenotype in Cancer” AKC Canine Health Foundation Co-PI $235,399
• “Outcomes assessment of the use of case-based writing exercises in veterinary clinical pathology”, College of Veterinary Medicine Educational Development Grants Program. Primary Investigator June 2009-December 2010, $4,250.

Honors and Awards