Electron Microscopy Techniques and Applications

Transmission Electron Microscopy

• Negative staining for pathogen identification:

• Viruses
• Protozoa
• Bacteria
• Fungi

• Tissue ultrastructure (tissue embedding):

• Infectious diseases 
• Tumor diagnosis
• Metabolic diseases
• Toxic diseases
• Immune-mediated diseases
• Inherited diseases
• Renal diseases
• Skin diseases
• Neuropathology

• Immunocytochemistry:

• Negative stain
• Embedded tissue

Scanning Electron Microscopy

• Parasites:

• Alveolates (Dinoflagellate, Aplicompexans)
• Amebozoan
• Metazoan

• Bacteria
• Fungi
• Algae
• Animal tissue